Purpose: The relation between smoking tobacco and dental caries has been the topic of research for quite some time. Varied association is presented in literature. A systematic review was conducted to analyse the relationship between smoking tobacco and dental caries. Methods: For the purpose of the review, only observational and prospective studies were selected. No case reports, reviews and letter to editors were excluded. All the studies measured dental caries using the DMFT index and the habit of smoking tobacco was self reported. Results: All the 9 articles appraised presented an increased risk of dental caries in smokers. Conclusion: A definite association was established between smoking tobacco and the increased risk of dental caries. Extensive research is needed to guarantee the causal relationship between the two variables.