Introduction: Breast cancer occurrence in India has rapidly risen to overtake cervical cancer in terms of incidence as well as mortality. Breast cancer is considered to be a complex disease demonstrating heterogeneity at clinical and histopathological levels. We believe that Breast cancer in the Indian population could be biologically different from those of the west. We attempt to study the clinical & pathological aspects of breast cancer with comparison to the western population in order to find pattern of differences. Materials and methods: All patients diagnosed and treated in the department of surgical oncology, King George Medical University, Lucknow, UP from the period of August 2014 to August 2016 are included. Clinical and histopathological data was recorded. Results: A total of 355 patients were analyzed. Average age of patients with disease was 45.3yrs. The premenopausal group consists of 52% of patients. Mostly patients presented in locally advanced stage. Conclusion: As compared to the western population the breast cancer in India presents in younger, premenopausal, multiparous and breast feeding women. They present in locally advanced stages with higher nodal positivity rates. It appears to be that breast cancer in India is a different subset from the western world in having different molecular signatures that translates into distinct clinical and histopathological subgroup.