Patient 65years came with chief complain of upper and lower limb weakness and on nerve conduction test diagnosing Guillen Barre syndrome. Patient was given intravenous immunoglobulin (IvIg) and presented with abdominal pain over left side, nausea and vomiting. On investigation HRCT showed splenic infarct. making this a contributor to splenic infarct and a rare complication of an approved method of treatment