Sirenomelia was first described by Rocheus in 1542 and Palfyn in 1553 and named after the mythical Greek God sirens1. This rare syndrome has the incidence of 0.8–1 case/100,000 births with male to female ratio being 3:12. We here report a rare case of primigravida with 28weeks of pregnancy who delivered a live sirenomeliac baby with identifiable risk factors being Cytomegalovirus (CMV) Infection (raised titres), Toxoplasma IgG avidity positive, Hypothyroidism, Vitamin D deficiency and herbal infertility treatment taken by male partner. The baby had typical potter facies, fused legs typically Sirenodipus and no external genitalia.