Pituitary macroadenomas are the most common suprasellar mass in adults, and responsible for the majority of transsphenoidal hypophysectomies. They are defined as pituitary adenomas greater than 10 mm in size and are approximately twice as common as pituitary microadenomas. On imaging attenuation and signal characteristics can significantly vary depending on tumor components such as hemorrhage, cystic transformation or necrosis.We report a rare case of invasive pituitary macroadenoma complicated by fatal intracranial hemorrhage in a 22 year young female presenting with headache, vomiting and convulsions.