Kawasaki disease is an illness that causes inflammation of the blood vessels in the body, which mainly involves medium sized arteries and veins. It is usually categorized by a varied number of symptoms, primarily of which consists of fever and platelet disorders. The latter manifests, in most cases as either thrombocythemia (increased platelet levels) or thrombocytopenia (decreased platelet levels). The incidence of thrombocytopenia is seen to be marked by coronary artery aneurysms. Research has shown that the levels of increased platelets (marked by elevated serum levels of thrombopoeitin during the third phase of Kawasaki disease), however exceeds that of the decreased platelet count. Fever also serves as a concurrent factor in the manifestation of Kawasaki disease as seen in the case study. It involves two case presentations, an 18 month old male child and a 4 year old male child with laboratory findings and results that explains in details, the valid need of the illumination into the basic symptoms presented in this study.