Clozapine is an atypical antipsychotic drug which is prescribed for treatment–refractory schizophrenia.1 The risk of adverse hematologic, cardiovascular, and neurologic effects has tempered its use, and reports of overdoses remain rare.2 Literature is relatively silent on antipsychotic overdose–induced coma. A few studies have so–far documented this rare neuropsychiatric presentation, and all of them were from western countries. We present the first ever report of clozapine intoxication leading to about 36 hours of coma in an adult man from western India.