Persistent Pupillary membrane (PPM) from various age groups and different presenting features attended outpatient department in a tertiary care centre. PPM was associated with cataract in two cases and superadded with features of chronic uveitis in one. One patient had developed amblyopia. Two cases were managed conservatively and one managed surgically by membranectomy with cataract extraction giving good postoperative result in terms of visual acuity and pupillary appearance. Cataract extraction in such patient posed risk of excessive postoperative inflammation, hyphema, pigment release from iris, transillumination defects and eventually glaucoma. All patients were followed up over a period of 15 months.