Background: Prostatic carcinoma is an important growing health problem, presenting a challenge to surgeons. Prostatic carcinoma is one of the most important causes of mortality in elderly men mainly because of the late detection despite of the fact that it is a potentially curable disease. Fine needle aspiration cytology (FNAC) is an easy to perform outpatient procedure requiring no expensive equipment or anesthesia. Objectives– The present study was carried out in an attempt to evaluate the effectiveness of fine needle aspiration cytology in the diagnosis of prostatic lesions. Materials and Methods:The present study has been performed on the fifty (50) patients, admitted in the surgical wards of , ESIC Hospital Basaidarapur New Delhi 2018–2019 with complaints of LUTS, in whom there was found to be a suspicion of malignancy of the prostate gland, in the form of palpable nodule or area of induration, during digital per rectal examination.. Results: Out of 32 cases of BPH on core biopsy, 29 cases were diagnosed as BPH on FNAC, 2 were diagnosed as adenocarcinoma on FNAC and FNAC of 1 case was not available. So accuracy of FNAC for BPH was 90.62%. accuracy of FNAC for adenocarcinoma was 70.00%. Conclusion: FNAC is a very useful, simple, cheap, repeatable technique in diagnosing accurately the prostatic lesions and can avoid an open biopsy in many cases reducing patient morbidity and increasing cost effectiveness of the treatment.