Endodontic periodontic lesions often creates dilemma to the clinician in making final diagnosis and treatment plan. In cases where there is severe destruction of one root of a tooth due to caries, splitting of the two roots and removal of one root along with associated crown structure is considered as a treatment modality.In cases where there is caries extending upto pulp associated with severe bone loss, bone augmentation of infrabony defect can be done ,following the initial endodontic phase of root canal treatment.In this case report root canal treatment was performed on both, endoperidontally involved mandibular first and second molar .Hemisection of distal root of 47 was done ,following which the infrabony defect persistant in 46 was augmented using CEM (calcium enriched mixture)cement and PRF.