IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-11-23316 Original Research Paper Study of Intrathecal fentanyl and butorphanol as an adjuvant to Intrathecal bupivacaine in infra- umbilical surgeries DEVASHRI CHILKE Dr. DR ANKIT SHRIVASTAVA Dr. November 2019 8 11 01 02 ABSTRACT

Present study was conducted in the department of Anaesthesiology in Durgapur Steel Plant Hospital, Durgapur, West Bengal. GROUP A (F)– 55 patients who were received intrathecal 0.5% hyperbaric bupivacaine 3ml with fentanyl 25 microgram (0.5 ml) total 3.5ml [n=55].. GROUP B (B)– 55 patients who were received receive intrathecal 0.5%hyperbaric bupivacaine 3 ml with butorphanol 250 microgram(0.25 ml) by insulin syringe and normal saline 0.25 ml (total 3.5 ml) [n=55]. We found that in Group–A (F), 34(61.8%) patients had highest sensory level T6 and 21(38.2%) patients had highest sensory level T8. 35(63.6%) patients had highest sensory level T6 and 20(36.4%) patients had highest sensory level T8. We found that in Group–A (F), the mean of time spinal drugs to sensory level (mean±s.d.) of patients was 1.5091 ± .5045 mints. In Group–B (B), the mean of time spinal drugs to sensory level (mean±s.d.) of patients was 1.4727 ± .5039 mints. In Group–A (F), 4(7.3%) patients had pruritis. In Group–B (B), 2(3.6%) patients had pruritis. Association of pruritis in two groups was not statistically significant (p=0.4010).In Group–A (F), 5(9.1%) patients had nausea& vomiting. In our study, We concluded that both fentanyl and butorphanol along with bupivacaine, provided adequate anesthesia and analgesia; but significantly lesser analgesic requirement was observed in the group receiving intrathecal butorphanol and bupivacaine mixture compared to intrathecal fentanyl and bupivacaine mixture.