IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-1-23724 Original Research Paper A PROSPECTIVE STUDY ON THE EFFECTS OF TOPICAL TESTOSTERONE IN MANAGEMENT OF DISTAL HYPOSPADIAS Prabhat Kumar Dr. Dr S.K. Sinha Dr. Dr Md Habibullah Ansari Dr. January 2020 9 1 01 02 ABSTRACT

Objectives: The aim was to evaluate the effect of topical testosterone on penile length, preputial hood, vascularity of dartos pedicle in patients with distal hypospadias. Materials and Methods: A total of 42 patients patients with distal hypospadias were included in this study. All were randomly allocated to 2 groups before surgical correction. Group 1 did not receive any treatment and group 2 received 1% testosterone propionate ointment twice daily for 30 days before surgery. Increase in penile length, transverse preputial diameter, and diameter at the base of penis were noted. Results: Following topical testosterone application, the mean increase in penile length, transverse preputial width and diameter at the base of penis was 1.01 ± 0.25 cm, 1.250 ± 0.52 cm and 0.61 ± 0.35 cm, respectively. Conclusion: Testosterone increased phallus size, diameter and prepuce hypertrophy without any adverse effects.