Objective: To assess oral health status and treatment need among mentally disabled subjects of Indore city. Materials and Method: A cross–sectional survey was conducted in disabled institution of Indore, (M.P.). Convenient sampling was employed to select a study sample of 120 mentally disabled subjects aged 12–22 years. Mentally disabled individuals diagnosed for conditions like cerebral palsy, Down’s syndrome or Autism were included in the study. The residential and family information was obtained from the participating special children schools. A home visit was then scheduled to collect the data on demographic variables, oral hygiene practices and clinical examination. Dentition status, Community periodontal index (CPI) and Dean’s fluorosis index was recorded using WHO 1997 proforma. Descriptive statistics and analytical tests like chi–square test, one way ANOVA was employed to compare the oral health status among the types of disabilities. Results: The overall prevalence of dental caries among the participants was 82.5 percent with a mean DMFT of 1.68 ± 1.18. Individuals with cerebral palsy showed higher DMFT (1.98±1.14) compared to autistic (1.77±1.23) and Down syndrome individuals (1.10±1.04) (p<0.05). About 54% of participants exhibited calculus deposits and shallow pockets were seen in 5%. The fluorosis experience was very minimal limiting to mild fluorosis in 2% participants. Conclusion: The caries experience of mentally disabled individuals was very high. Individuals with Cerebral palsy had the higher caries level than other categories of mental disability. Gingival Bleeding and calculus deposits are more. Unmet treatment need has to be addressed among this population.