IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-1-23770 Original Research Paper Outcome of Immediate Post-operative Injected Platelet-rich Plasma Therapy After Follicular Unit Extraction Hair Transplant: A Prospective Randomised Study in Fifty Patients Monali Makadia Dr. January 2020 9 1 01 02 ABSTRACT

Aims and Objectives: The objective of this study was to study efficacy of injectable PRP therapy in follicular unit extraction (FUE) hair transplant. Method: It is a prospective randomised study on 50 FUE hair transplant subjects, allocated in two groups (PRP and non–PRP) alternately. PRP was injected immediately post–operatively over the recipient area in PRP group; and normal saline in non–PRP group. Two groups were evaluated at 3, 6 and 9 weeks, 3 and 6 months of the procedure. Statistical analysis: It was done using Chi–square test and test of significance was set as P < 0.05. Results: In PRP group, all subjects had >75% hair regrowth at 6 months, density of >75% grafts was noticed in 15 patients at 6 weeks meaning reduced fall of transplanted hair during catagen phase. New hair growth started at 8 weeks in 12 patients and redness over recipient area completely disappeared in 20 patients at 3 months of surgery and activity in dormant follicles as fine thread like hair was noticed besides the thick transplanted hair in all subjects. In non–PRP group, five patients had >75% hair regrowth at 6 months and none showed >75% graft density at 4 weeks. Conclusion: Intra–operative PRP therapy is beneficial in giving faster density, reducing the catagen loss of transplanted hair, recovering the skin faster and activating dormant follicles in FUE transplant subjects.