IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-1-23778 Original Research Paper A CROSS-SECTIONAL STUDY TO STUDY THE ASSOCIATION OF VITAMIN D LEVELS WITH GLYCOSYLATED HEMOGLOBIN LEVELS IN ELDERLY OF BANGALORE CITY Jyothi Vybhavi V.S. Dr. January 2020 9 1 01 02 ABSTRACT

Background: Ageing is a natural process and healthy ageing has become a growing global challenge. The process of ageing affects nutritional needs, they are particularly prone to inadequate intake of VitaminD. Vitamin D is suggested to influence glucose homeostasis. An inverse relationship between serum 25‐hydroxyvitamin D (25[OH]D) and glycemic control with type 2 diabetes was reported in previous studies. Hence this study was undertaken to investigate the association between vitamin D and Glycosated Hemoglobin levels in elderly of Bangalore city. Objectives: A. To estimate Serum Vitamin D levels in the elderly. B. To estimate Glycated Hemoglobin Levels in the elderly C. To correlate the Vitamin D levels with Glycosylated Hemoglobin Levels in the elderly of Bangalore city. Methodolgy: This study involved 80 healthy elderly subjects with consideration of inclusion and exclusion criteria. Written informed consent was taken. For each subject, fasting blood sample of 4ml was collected for Serum 25(OH) Vitamin–D assessment and Glycosylated Hemoglobin levels. Anthropometric measurements were taken. 24–hour dietary recall, General history questionnaire were administered. Results were compiled and statistically analyzed. Results: Serum 25(OH)D levels were inversely associated with A1C levels. These results are after adjusting for age, sex, A1C, BMI, treatment and duration of diabetes. Conclusion: It can be concluded that Low Serum Vitamin D levels were associated with higher Glycosalated Hemoglobin levels warranting the need for educating the senior citizens the importance of Vitamin D and its supplementation for a Healthy Ageing.