Circulating testosterone level is high in PCOS. The source of testosterone is either ovary for adrenal or both. In ovary androgen production is controlled by LH. Where LH is excessive and FSH is suppressed, this results in an imbalance leading to increased androgen production with normal or suppresses oestrogen production; particularly oestradiol. Extensive evidence confirms that adrenal androgen excess is also common in PCOS. The aim of the present study is to estimate the serum androgen level in patients of PCOS & control group. Significant elevation of plasma Androgen level is observed in PCOS cases then normal control group. This will help to understand the pathophysiology of polycystic ovarian disease.