IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-1-23872 Original Research Paper MATERNAL AND PERINATAL OUTCOME IN PRETERM PREMATURE RUPTURE OF MEMBRANES Velpula Srilakshmi Dr. January 2020 9 1 01 02 ABSTRACT

Background: This is a prospective observational study carried out in department of Obstetrics and Gynecology, in ASRAM Medical college, Eluru to determine the factors influencing fetal and maternal outcome, prognosis and complications in preterm premature rupture of membrane cases. Methods: The present study is a prospective observational study of perinatal and maternal outcome in 50 cases of preterm premature rupture of membranes in between 28 to 37 weeks of gestation with singleton pregnancy, from December 2018 to November 2019. Patients with medical complications like anemia, pre–eclampsia and eclampsia, diabetes mellitus, vascular or renal disease, polyhydramnios, multiple gestations, uterine or fetal anomalies etc. are excluded from the study. Detailed history, general physical examination, abdomen and pelvic examination were carried out. Results: In this study, 54% of cases are primigravida and 46% of cases are multigravida. Patients belonging to low socioeconomic status accounts for 60%, and middle socioeconomic status for 38%. Perinatal morbidity is seen in 70% and most common causes are RDS( 18%), sepsis(22%) and hyperbilirubinemia (26%).Twenty–three neonates(46%) were delivered by caesarean section. The main indications for caesarean being fetal distress( 43.4% ). Conclusions: PPROM is one of the important causes of preterm birth that can result in high perinatal morbidity and mortality along with maternal morbidity. The most common cause of perinatal mortality in early PPROM is prematurity and its complications. In late PPROM perinatal outcome is good.It is suggested that timely diagnosis and management of PPROM is critical to optimize perinatal outcome and minimize neonatal morbidity.