Introduction: Catheter associated UTI is common hospital acquired infection due to widespread use of urinary catheter. Objectives: 1. To know the occurrence of CAUTI in ICU of our hospital. 2. To know the bacteriological profile and antibiotic sensitivity pattern of the isolates. Materials and Methods: All consecutive urine samples of catheterized patient who are admitted in ICU for more than two days have been collected and processed for culture & antibiotic sensitivity. Results: In our study 155 samples were processed. Occurrence of CAUTI in our ICU set up was 21 %. Among 155 samples in 33 sample bacteria were isolated . Most common isolates were Escherichia coli (30%) Klebsiella spp. (20%) & Enterobacter spp. (13.3%) followed by Pseudomonas spp. (13.3%), MRSA (9.09%) & Enterococcus (9.09%). Most of the isolates were multidrug resistant. Conclusion: Urinary tract of catheterized patient is highly susceptible to infection, when duration of catheterization is prolonged. Isolates are usually multidrug resistant. There should be judicious use of urinary catheterization only when indicated as well as for minimum time interval.