OBJECTIVE: To evaluate the new method of sonoelastography which could improve the differentiation and characterization of benign and malignant breast lesions in comparison with the Mammosonography. METHODS AND MATERIALS: From January 2016 and December–2017, 50 consecutive patients were diagnosed as benign or malignant by mammosonography and further analyzed with sonoelastography. The diagnostic results were evaluated with histopathologic findings. The sensitivity, specificity, positive and negative predictive values were calculated for each modality and the combination of sonoelastography and mammosonography. RESULT: Of 50 lesions, 17 were histologically malignant, and 33 were benign. On the examination of benign and malignant lesions, the shape of the mass was described as oval or round (57.5% and 70.5%), margin as circumscribed (69.6% and 58.8%). Fibroadenoma was the most common benign lesion and ductal carcinoma was the most common malignant lesion noted in our study. The sensitivity, specificity of mammosonography was 69.7%, 70.59%, and sensitivity, specificity of with sonoelastography was 81.82%, 88.24% in our study. CONCLUSION: Using elastography, a more accurate preoperative diagnosis can be made, thereby, obviating the need for aggressive biopsy in cases of benign lesions and improve the number of positive breast biopsies.