AIM– To compare and analyze the variations in Blood Pressure and Hemoglobin during the pre and post–operative period in patients undergoing On–pump and Off–pump CABG. SAMPLES– This observational comparative study was conducted among 242 patients (121 each group). RESULTS– Post Systolic and Diastolic Blood Pressure are found to be increased on both the techniques. This post CABG hypertension usually comes to normal 4 to 6 weeks after the surgery. In majority of patients Hemoglobin (Hb) level is found to be reduced postoperatively on both the techniques of doing CABG. CONCLUSIONS– Post CABG results of SBP, DBP and Hb levels showed almost similar outcomes among both the techniques of performing CABG. The main observation noticed in this study is the post CABG Hb level, which is found to be lower in females than from males.