IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-2-24055 Original Research Paper A comparative clinical study of anaesthesia with isobaric Levobupivacaines in cases undergoing lower limb surgeries under spinal anesthesia or peripheral nerve blocks. Shanker Malviya Dr. Amar Singh Chandrawal Dr. February 2020 9 2 01 02 ABSTRACT

Levobupivacaine is long acting local anaesthetic drug introduced in practice. The study has been made to compare the anaesthesia produced by this drug used in two different techniques – subarachnoid block or peripheral nerve blocks . Methodology – A prospective, comparative, randomised , double blind clinical study was carried in S.R.N. hospital , Allahabad (Prayagraj) over a period of two years after approval from ethical committee of the institution . Sixty patients belonging to physical ASA 1 or 2 having cardiovascular or respiratory diseases (well controlled with medication ) , aged 18–60 years undergoing lower limb surgeries were included . Two groups A and B of thirty each were made .Group A received 3ml isobaric Levobupivacaine 0.5% in subarachnoid block , Group B received combined sciatic–femoral nerve blocks ( along with Obturator and Lateral Cutaneous nerve of thigh block when required) given with same drug . Observations for onset, quality, duration of sensory and motor blocks ; pulse , BP , electro cardiography and SpO2 were made. Rapid onset of sensory and motor blocks was observed in patients given spinal (p < 0.05). Postoperative analgesia was longer in patients given nerve block (p < 0.05) . Quality of anaesthesia in both groups was good. There was fall in blood pressure at 1 and 4 hour in few cases in spinal group (p < 0.05). Both groups showed stable vital parameters .Conclusion – Anaesthesia was good , safe and comparable with both techniques. Post operative analgesia was additional advantage with nerve blocks which added to patient’s satisfaction . Future work – The study can be further extended to patients havings co morbidities where safety of anaesthesia is a concern.