There is an increasing prevalence of diabetes during pregnancy globally, and this is associated with an increased risk of complications in both mother and fetus. The aim of this research is to study the neonatal complications of maternal diabetes. This was a prospective cohort study that was conducted in DR.PSIMS & RF hospital, Gannavaram, between December 2017 to May 2018. All infants born to diabetic mothers during the study period were monitored. Data on sex, gestational age, and birth weight, mode of delivery, complications, investigations, birth injury, and length of hospital stay were recorded. Maternal data were retrieved from records. Data was analyzed using SPSS (Version 16) for M.S.Windows. A total of 33 infants of diabetic mothers (IDMs) were included in the study. 17 infants (51.5%) were females and 16 (48.4%) were males. 18 (54.5%) of the neonates were born by caesarian section and 15 (45.5%) were born by spontaneous vaginal delivery. 16 (48.5%) of the neonates were preterm and 17 (51.5%) were born term. 4 (12.1%) of the babies were large for gestational age (LGA) and 1 (3%) was macrosomic. Congenital anomalies were found in 3 (9.1%), hypoglycemia in 7(21.2%), hyperbilirubinaemia in 23 (69.7%), hypocalcaemia occurred in 4(12.1%), transient tachypnea of the newborn occurred in 1 (3.0%) of the neonates. No significant birth injury or birth asphyxia, mortality were noted. We concluded that, hyperbilirubinemia, prematurity, hypoglycaemia were the commonest complications in IDMs and maternal glycaemic control was found to have a significant effect on the morbidity of an infant born to diabetic mother.