IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-2-24138 Original Research Paper Epidemiological, clinical, Dermoscopic and Histopathological evaluation of striae K. Anitha Dr. Dr. Sushma Malladi Dr. Dr. D Subba Rao Dr. February 2020 9 2 01 02 ABSTRACT

Introduction: Striae or stretch marks were described as a clinical entity since long which are undesirable and etiopatho genitically ill understood clinical entity. Here is the study describing “Epidemiological, Clinical, Dermoscopic and Histopathological features” in patients presenting with striae. Aims and objectives: 1.To know the epidemiology and clinical patterns of different types striae. 2. To evaluate the dermoscopic features of striae. 3. To evaluate the histopathological features striae. Materials and methods: 1.Source of data: A hospital based, cross sectional, descriptive and analytical study in epidemiological, clinical, dermoscopic and histopathological features of striae was conducted in Department of Dermatology,Venereology and Leprosy, ASRAM, Eluru, AP. 80 Patients were recruited from OPD and study was conducted from December 2017 to August 2019. Dermoscopy, 3 punch biopsies, H&E Staining and special staining were done in selected cases. Results: Of the 80 cases studied, 50% were males and 50% were females with sex ratio being 1:1. The age group in which striae occurred more frequently was 11–20yrs with 52.7%. The mean duration of striae is (13.46months ±20.16)months. Exercise, sudden weight gain, positive family history and topical steroid misuse were most common risk factors. Types are according to the risk factors and subtypes are by their color, morphology, dermoscopy and histopathology. Length, breadth, shape and degree of atrophy differentiates them morphologically. Color, vascularity and melanisation patterns differentiates them dermoscopically. Degree of melanisation, perivascular infiltration , dermal oedema, degree of damage of collagen and elastin differentiates them histopathologically. Conclusion: Most common age group involved in development of striae is 11–20yrs with equal sex ratio with various differences in clinical, dermascopic and histopathological features.