BACKGROUND: e–Learning is defined as acquisition of knowledge and skill using electronic technologies such as computer, Internet, local and wide area networks. In diverse medical education contexts, a developing infrastructure to support e–learning is necessary to acquire knowledge by the medical students. In this study an endeavor was made to assess the awareness of medical students to e–learning. OBJECTIVE: To assess the Knowledge, Attitude and Practices of Medical undergraduate students towards e–learning. METHODOLOGY:This is an institutional based, analytical cross sectional study. Data was collected from medical undergraduate students (n=250) of third and fifth semesters using a convenient sampling method. A predesigned questionnaire was used for study. The data was analyzed using SPSS 23 trial version. RESULTS:Among the study subjects, 97.2 p.c were aware of e–learning and also utilizing e–learning facility. 82.8 p.c were using e–learning for reference purpose only and 75.6 p.c prefer a mix of both e–learning and traditional learning. The most common mode of learning (64.8%) was by watching videos and 44.8 p.c of the students were visiting YouTubefor e–learning. 57.2 p.c felt that access to internet was a barrier for using e–learning for them. About 48 p.c said that they were spending 5–30 minutes on e–learning. CONCLUSION: The KAP among medical undergraduates regarding e–learning was satisfactory. Hence, they can be taught and encouraged to use different modes of e–learning for better academic performance.