IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-3-24328 Original Research Paper Effect of adding ultra–low–dose Naloxone to Fentanyl and Lidocaine combination for peribulbar anesthesia C.Vairavarajan Dr. March 2020 9 3 01 02 ABSTRACT

Successful peribulbar block with adding adjuvants like fentanyl and naloxone in ultra–low dose will provide a safe, quality of anaesthesia intraoperatively and good and prolonged postoperative analgesia. We conducted a randomized double blinded study to evaluate the quality of the block and the duration of postoperative analgesia when ultra–low–dose of naloxone added to fentanyl and lidocaine for peribulbar anesthesia. There was no significant difference between the two study groups regarding the total injected volume, onset, and best akinesia score. Adding low dose naloxone with fentanyl significantly prolong post op analgesic duration without altering onset , quality and duration of block without any significant side effect.