Introduction: Neonatal Seizures is still a common global health problem despite huge growth in healthcare sciences, difficult to diagnose and treat, associated with higher rate of morbidity and mortality. The purpose of this study was to find the commonest etiological factors of neonatal seizures in this region and determining its outcome. Materials and Methods: A total of one hundred and four neonates presented with seizures were advised to undergo required investigations. Detailed clinical history and examination findings were noted. Results: Incidence of neonatal seizures is 11.9%. Out of 104 neonatal seizures, 58 (55.7%) were females and 46 (44.2%) were males. Majority of neonates had seizures in first three days, it was 67.3%. Predominant cause was birth asphyxia and 23% had septicaemia. Mortality rate was 16.3%. Conclusion: Most of the etiologies of neonatal seizures can be rapidly reversed by appropriate management and also long term sequelae can be prevented.