IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-3-24408 Original Research Paper A COMPARATIVE STUDY OF INTRAVENOUS DEXMEDETOMIDINE AND INTRAVENOUS TRAMADOL FOR POST SPINAL ANAESTHESIA SHIVERING Pal Nehra Dr. Omprakash Nagar Dr. March 2020 9 3 01 02 ABSTRACT

Introduction: Shivering is a natural protective phenomenon. The main causes of intra/post–operative shivering are temperature loss, increased sympathetic tone, pain, and systemic release of pyrogens. Spinal anaesthesia significantly impairs the thermoregulation system by inhibiting tonic vasoconstriction, which plays a significant role in temperature regulation. Several drugs have been studied for the prophylaxis as well as treatment of shivering. Tramadol, an opioid receptor agonist, has also proved to be effective in the treatment of shivering after general anesthesia, On the other hand Dexmedetomidine, a congener of clonidine, has been used as a sedative agent and is known to reduce the shivering threshold. The aim of the study was to compare the efficacy of dexmedetomidine and tramadol in the treatment of post–spinal anesthesia shivering as well as their side–effect profile. Materials and methods: The present study was carried out in the Department of Anaesthesiology and Critical Care, Government Medical College, Kota. This is a Prospective Randomized Comparative Study. Patients aged 18–65 years, American Society of Anesthesiologists I & II and scheduled to undergo elective surgeries under spinal anesthesia and developing shivering grade 3 or grade 4 were included in the study. We made two groups of cases i.e. Group T (TRAMADOL) and Group D (DEXMEDETOMIDINE). sample size was 64, which was divided into two groups of 32 each. Standard protocol followed to administering spinal anaesthesia. On occurrence of shivering its intensity graded using a four point scale as per Wrench.. All data were collected and analysed with the help of suitable statistical parameters. Results: Our study results in that dexmedetomidine is more effective in the treatment than tramadol for treatment of postspinal anaesthesia shivering