AIM: This study was undertaken to determine the acute changes in IOP following laser photocoagulation used in the treatment of diabetic retinopathy. METHODS AND METHODOLOGY: This study was conducted at the Department of Ophthalmology, Chalmeda Ananda Rao Institute Of Medical Sciences from July 2017 to June 2018 . This study was intended to see the onset and duration of intraocular pressure spikes in diabetic retinopathy patients after green laser photocoagulation. RESULTS: Out of 45 patients, 6 patients had severe non proliferative diabetic retinopathy with maculopathy, 39 having proliferative DR. Out of 6 NPDR patients, 3 (50%) developed immediate post laser angle closure (Schaffer‘s grade 1) which persisted for 3 days and other 3 had shown no change in angle structure. Out of 39 PDR patients, 12(30.7%) had post laser angle closure.These results are clinically and statistically significant.Overall 33.33% of patients showed raised intraocular pressure following PRP. CONCLUSION:The present study clearly shows that after extensive laser photocoagulation in diabetic retinopathy patients, elevation in IOP may appear immediately or 1–2 hours or 1–2 days later and this last for 2–3 days