Introduction: Serous effusions are frequently encountered clinical manifestation of the underlying disease process and their cytological examination is a cheap rapid and highly informative laboratory procedure Material & Methods: A total of 83 different body fluids aspirated were evaluated in the cytology section of the department of pathology Government Medical College Jammu from Dec 2018 to Jan 2020. Results: Peritoneal fluid was most common aspirated fluid 53.01% followed by pleural fluid 33.73% with a M:F ratio of 1.8:1. Maximum cases belong to the age group of 30–40 years. Out of 83 total fluids aspirated 69 (83.13%) were benign and 14 (16.87%) were malignant. Among the malignant effusions 8 (57.14%) were Adenocarcinoma followed by 2 cases (14.29%) each of squamous cell carcinoma and Non Hodgkin’s Lymphoma and 1 case (7.14%) each of Small Cell Carcinoma and Acute Lymphoblastic Leukemia. Conclusion: Cytologic evaluation of serous fluids is a simple and useful procedure in making diagnosis and understanding the course of disease