Background: Dental caries is one of the severe disease which leds to irreversible loss of tooth structure. Caries removal my means of rotary is quick but, it also may damage healthy tooth structure. Chemomechanical caries removal agent is an excellent alternative in removing caries, by not only reducing bacterial count but also remineralizing tooth structure. Material and method: A total of 40 primary molar teeth (n = 40) were divided into two groups of 20 teeth each. In the first group, caries was removed using Brix 3000 and in second group caries was removed using V– Carie – Solve. Caries samples were collected in sterile vials containing 1ml of saline before and after application of CMCR gel. Excavated dentin samples were vortexed in microbiological lab followed by inoculation on blood agar aerobically for 24 h, and total viable count (TVCs) were determined and expressed as colony forming units per sample. Result: Mean reduction of TVC of bacteria was seen in both the group, but was more significant in Brix–3000. Conclusion: The advent of Papacarie® gel has revolutionized the chemomechanical caries removal process and has proved to be a highly effective and excellent product with added advantage of maximum preservation of healthy tooth tissue, especially in cases of deep dentinal caries