IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-3-24595 Original Research Paper An Observational Study of Gastric and Intestinal Perforations in a Tertiary Care Centre in Central India Prasad Upganlawar Dr. Dr Ashwinee Rahalkar Dr. March 2020 9 3 01 02 ABSTRACT

Peritonitis due to perforation of viscous either post traumatic or nontraumatic is an important cause of morbidity and mortality in an emergency. Peptic ulcer is one of the most common malady that affects the Indian population. Perforation of gastric or duodenal ulcer is one of the most serious and most overwhelming catastrophic that is affecting human being. The following study was conducted with the intent of finding the relative frequency of anatomical site of perforation, the relative causes implicated in the etiology for perforation and the complication in the outcome of perforation. This was a clinical observation study conducted in a Tertiary Healthcare Centre in Central India between 1/7/2018 to 30/6/2019. A total of 104 were enlisted, after satisfying the inclusion criteria for this study with a male to female ratio of 6:1. Epigastric pain was the most common symptom reported. After thorough evaluation and resuscitation, open exploration was done for all patients. Duodenal ulcer perforation was seen in majority of the patients, the cause being peptic ulcer disease. Post operatively, all were given anti H. pylori treatment. Complications were reported in 39 patients post operatively and there were 6 deaths in the post operative period. A total of 59 patients recovered without any complication in the post operative period. LRTI was the most common complication noted. The mortality was higher in those patients who reported more than 24 hours after onset of symptoms.