Introduction: Coronary artery disease (CAD) will be the leading cause of mortality by 2020. During recent years, many studies are directed towards the evidence that the concomitant occurrence of hyperglycemia in patients with an acute myocardial infarction (MI) enhances the risk of mortality and morbidity, with or without diabetes. Aims and objectives: To determine the relationship of admission blood glucose levels and in hospital mortality in non–diabetic myocardial infarction patients. Materials and method: A study of 100 cases non–diabetic acute myocardial infarction patients was carried out in the Medicine department, Guru Nanak Dev Hospital attached to Government Medical College, Amritsar. Patients were divided among four groups according to admission blood sugar level. Group I (≤120 mg %), Group II (120–139 mg %), Group III (140–179 mg %) and Group IV (>180 mg %). All cases were examined and investigated and followed up for any complication like cardiogenic shock or death during their hospitalization period. Data derived was analyzed using appropriate statistical methods across the groups. Conclusion: It was concluded from the study that even in non–diabetic patients, hyperglycaemia on admission is independently associated with a higher risk of in–hospital mortality.