IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-5-25026 Original Research Paper A study to compare Intravenous bolus Phenylephrine and ephedrine in controlling Hypotension under Spinal Anaesthesia for Caesarean Sections Ghasiram Agrawal Dr. May 2020 9 5 01 02 ABSTRACT

Introduction : Spinal anaesthesia is more acceptable method of anaesthesia in elective cesarean section, but hypotension is the major limitation of this technique which might trigger to serious complications for both mother and fetus. The use of vasopressors is necessary to control hypotension caused by spinal anaesthesia. The present study was designed to compare the vasopressor effects of ephedrine and phenylephrine in ameliorating hypotension in elective caesarean delivery Methods: This was a Retrospective study . Data of 100 Cases of Caesarean Section surgeries were selected which used Ephedrine and phenylephrine as Vasopressors during Spinal Anaesthesia in last 2 years. Randomization was done using computer tables in selecting data. Patients were randomly allocated into two groups of 50 each. Randomization was done using computer tables in selecting data. The intergroup comparisons were made by Student‘s t–test and chi–square test for categorical variable. Results: There was no significant difference between different Age , height & BMI in two groups. The number of rescue doses required in group 1 and group 2 was statistically insignificant. The differences observed in baseline HR, SBP, DBP, and mean blood pressure between the two groups were statistically insignificant. There was a higher incidence of bradycardia in patients receiving phenylephrine. The difference in birth weight of neonates between the two groups was statistically not significant. No neonate had Apgar score <7 at 1 min and 5 min. Conclusion: In the present study, there was no statistically significant difference in the incidence of hypotension with rapid administration of crystalloid at the time of induction of spinal anaesthesia in both the groups (P > 0.05). We conclude from the present study that ephedrine and phenylephrine in appropriate equivalent doses are equally efficient in managing hypotension during spinal anaesthesia for caesarean delivery.