This study was conducted in a municipal medical college in Thane, Maharashtra state to determine the distribution of ABO and Rh blood types among medical students and compare the results with that of similar studies on medical students in India. Blood groups of 375 medical students – 195 (52%) females and 180 (48%) males – were analyzed. “B” blood group was the commonest blood group amongst the medical students (37.07%), followed by “O” (30.67%), “A” (21.07%) and “AB” (11.20%) blood groups, respectively. 95.47% medical students were Rh positive and 4.53% were Rh negative. The most prevalent pattern of distribution of ABO blood group types among medical students viz. (B>O>A>AB), was also found in the present study. Diversity in patterns of blood groups among Indian medical students may be attributed to the medical admission procedure, which indirectly contributes to heterogeneous genetic distribution of medical students