Macroglossia is a volumetric and morphological alteration of the tongue, caused by muscular hypertrophy, vascular malformation, metabolic diseases and idiopathic causes; usually associated with Downs and Beckwith–Wiedemannsyndrome. This alteration can cause dental–muscular–skeletal deformities, orthodonticinstability, masticatory problems and variation in taste and speech. In this article, we present a case of true macroglossia diagnosed in a male patient of age 25 years, with no significant family history, but he had a history of relapse of orthodontic treatment for the correction of open bite, proclined upper and lower anterior teeth. He further had a complaint of difficulty in phonation. We have performed partial glossectomy under general anaesthesia using the “Modified clove shape” technique, with an objective of reducing the length and width of the tongue. The patient had successfully extricated with no signs of paraesthesia at the apex of his tongue and has recovered without any alterations in his taste or motor sensation.