Objective; to evaluate the effect of Uroflometry parameters and post void residual urine on post trans rectal prostatic biopsy (TRPB) complications. Also to evaluate the effect of urinary tract infection (UTI) on acute urinary retention (AUR) after TRPB Material and methods; this was a prospective comparative study conducted from December 2016 till May 2019. Total 150 patients were included. Effect of various Uroflometry parameters on post TRPB complications was evaluated. Results; Post void residual urine (PVR) had a significant effect on acute urinary retention (AUR) (P–value 0.016 ), and febrile urinary tract infection (UTI) (P–value 0.016), while as peak flow rate (PFR) and average flow rate (AFR) did not have any significant effect on AUR and UTI after TRPB. Conclusion; Patients with significant PVR subjected to TRPB should be watched carefully for febrile UTI and AUR. Low PFR and AFR do not have a statistically significant effect on AUR and febrile UTI after TRPB if kept on Alfa blockers before TRPB.