This complete enumeration, cross–sectional study was conducted on first–year MBBS students at a municipal medical college. At the “procedure station”, observers with a pre–validated checklist awarded marks (two marks per correct procedural step; maximum = 20 marks). At the “question station”, the students attempted ten short–answer questions (two marks each; maximum = 20 marks). At the “procedure station”, the average score of female students (n=31) was 18.00 +/– 1.55, while that for males (n=48) was 17.83 +/– 1.69, without significant gender difference (Z=0.459; p=0.646). At the “question station”, the average score of female students was 14.97 +/– 1.30; while that for males was 14.15 +/– 1.87, exhibiting significant gender difference in scores (Z=2.297; p=0.021). The proficiency in performing the procedure (psychomotor domain) component of the practical was comparable but the cognitive domain scores of male students was significantly lower than that of their female counterparts.