The purpose of the present article is to provide an exhaustive review of the speculated applications of nanorobots for the diagnosis and treatment in dentistry. The introduction of nanotechnology in dentistry can augment the quality of dental health diagnosis and treatment to an unprecedented higher level. In this respect, the role of nanorobotics is worth mentioning. Nanorobotics is an emerging technology for creating microscopic machines or robots with dimensions nearly one nanometer (10−9 meters). Nanorobots are intelligent nanoelectromechanical systems having components such as on–board sensors, manipulators, motors, power supplies, and molecular computers. They are capable of intruding into the human body either through the vascular system or through catheters. From the review of the related articles, it was seen that nanorobots can have made revolutionary changes in dental disease diagnosis and treatment. They have high potential to function at the atomic, cellular, and molecular levels and can penetrate human tissue with navigational precision in response to its sensor stimuli, the preprogrammed instructions from onboard nanocomputer, and strategic orders of the dentist through signals. Its role is effectively extended to the field of anesthesia, hypersensitivity, Orthodontic treatment, Aesthetic dental treatment, oral cancer, oral hygiene, halitosis, etc.