IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-6-25446 Original Research Paper Prediction of recovery in Spinal Cord Injury - Case series from a tertiary spinal injury centre in North India Astha Patni Dr. Dr. Nitesh Kumar Goyal Dr. June 2020 9 6 01 02 ABSTRACT

Study design: Prospective Observational Study Objective: To find out the role of prognostic predictors of ASIA grade, Pin prick preservation and MRI finding for neurological recovery in traumatic spinal cord injury patients Setting: Patients admitted from 1st January 2007 to 31st January 2008 in the department of Physical Medicine & Rehabilitation, S.M.S. Medical College, Jaipur, India Method: Out of 467 cases of SCI admitted during the study period, 310 cases were excluded due to various reasons and remaining cases were neurologically evaluated as per the guidelines of American Spinal Cord Injury Association (ASIA). Neurological recovery was measured for ASIA grade as ASIA grade improvement; Pinprick [PP] preservation for segmental motor recovery; Magnetic Resonance Imaging [MRI] patterns for light touch [LT] score, PP score, Motor score and ASIA grade improvement. Results: At mean follow up of 5.82 months [3–17 months], in 157 SCI cases, ASIA grade improvement was observed in 21/21 [100%] cases of ASIA grade C versus 16/22 [72.73 %] cases of ASIA B; 12/32 [37.50%] cases of ASIA D and 17/82 [20.73%] cases of ASIA A. Functional motor recovery [> 3 grade] was observed in 264/377 [70.03%] segments having PP sensation 2/2; 35/87 [40.23%] segments having PP sensation 1/2 and 71/887 [8%] segments having PP sensation In MRI Compression pattern, ASIA grade improvement was observed in 2/3 [66.67%] cases of ASIA A, 1/1[100%] cases of ASIA C and 1/3 [33.33%] cases of ASIA D. In Cord contusion and edema pattern, ASIA grade improvement was observed as 1/1 [100%] cases of ASIA A, 3/3 [100%] cases of ASIA B, 1/1 [100%] cases of ASIA C and 2/3 [66.67%] cases of ASIA D. In Compression with cord contusion and edema pattern, ASIA grade improvement was observed as 12/46 [26.09%] cases of ASIA A, 8/12 [66.67%] cases of ASIA B, 17/17 [100%] cases of ASIA C and 2/14 [14.29%] cases of ASIA D. Hemorrhagic and Transection pattern had no ASIA grade improvement. Significant improvement in LT, PP and Motor score observed in compression with cord contusion and edema. Compression and hemorrhagic pattern had no significant improvement while cord contusion and edema had significant motor score improvement. Transection pattern had no potential for recovery for LT, PP and motor score. Conclusion: A fair prediction of neurological recovery can be done on the basis of prognostic predictors as ASIA grade, Pin prick preservation and MRI finding