Introduction: Malaria is a protozoan disease transmitted by the bite of infected Anopheles mosquitoes. Based on documented cases, the WHO estimates that there were 219 million cases of malaria in 2010 resulting in 660,000 deaths. This is equivalent to roughly 2000 deaths every day. present study was planned to study clinical and biochemical prognostic markers in malaria which will help in triaging of patients to ward/ICU according to severity of malaria and also to find out the probability of mortality among malarial patients. It may also help in predicting the prognosis of the patient. Aims and objectives: To Evaluate for Various Clinical and Biochemical Prognostic Markers in Malaria, To evaluate the relevance of GCSABL prognostic malarial score and To compare GCSABL prognostic malarial score to other prognostic malarial score (Mahapatra MK) . Materials and methods: The study was conducted among 300 adult patients of malaria (Pf, Pv, Pf+Pv) in department of Medicine at MLB Medical College from March 2018 to Aug 2019. Result: Patients who had GCSABL score in the range 6–10 were 30 (10%) , out of these 36 patients, 21 (70%) patients improved while 9 (30%) patient expired 13 (4.33%) patients had GCSABL score in the range 11–14, out of which 2 (15.38%) patients improved while 11 (84.61%) patients died. As the GCSABL score increased mortality increased in malarial patients. Conclusion: were classified as having uncomplicated malaria i.e. they did not have any serious complications. 59 patients had one or more complications and were classified complicated malaria. Uncomplicated malaria patients cumulative score (Mohpatra MK Das) <5 were successfully treated in ward settings. No patients died and develop any complications during treatment. Out of total 59 patients who were treated in ICU setting 20 patients died. As the GCSABL score increased mortality increased in malarial patients. So we can successfully triage malarial patients accordingly to GCSABL score & we keep up patients according to risk in resource limited facilities