The need for exercise both physical and mental, for the total well being of an individual, is no longer unknown to a common man. Physical exercise needs to be included as a routine in our day–to–day life, as the majority of us lead a sedentary life. Stress leads to the generation of free radicals in animal muscle as evidenced by direct measurements of free radicals with the electron paramagnetic resonance technique and by indirect determination of product of free radical reactions. Yoga practice is useful in the management of various lifestyle diseases type 2 diabetes, obesity, hypertension, and dyslipidaemia. In type 2 diabetic subjects increased brain glucose levels has been observed that alter the brain metabolites and may impair cognitive function. In study by Rajani et al. HbA1c levels were less in test group than in the controls, because yogasanas and pranayama normalized the increased plasma glucose levels by increasing the peripheral uptake of glucose or by increasing the pancreatic insulin secretion. This study clearly emphasize that yogasanas and pranayama has a positive effect on overall cognitive performance in type 2 diabetes subjects. The various postures during yoga practice help to improve the sensitivity of β–cells to glucose, thereby improving insulin secretion, and increase the blood supply to the muscle and muscle relaxation, thereby improving glucose uptake. Improvements in hormonal homeostasis also improve glycaemic control in people with diabetes mellitus . Yoga therapy also results in immunomodulation by reducing proinflammatory responses and improving immune function. (Rajni et al., 2017) Ttryambake (2015) had showed that the mean blood pressure on day 1 and day 10 shows the difference in systolic blood pressure was 21.33 mmHg and diastolic blood pressure was 11.54 mmHg after doing pranayam. Pranayama increases frequency and duration of inhibitory neural impulses by activating pulmonary stretch receptors during above tidal volume inhalation as in Hering Bruer reflex, which bring about withdrawal of sympathetic tone in the skeletal muscle blood vessels, leading to widespread vasodilatation, thus causing decrease in peripheral resistance and thus decreasing the diastolic blood pressure. This mechanism is supported by the fact that after hyoscine–N–butylbromide, the parasympathetic blocker, it was observed that blood pressure was not decreased significantly as a result of pranayama, as it was observed when no drug was administered. (Ttryambake., 2015)