IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-6-25589 Original Research Paper Hyperparathyroidism during pregnancy A Review Pushpalata Dubey Dr. Dr Chandra Mauli Upadhyay Dr. June 2020 9 6 01 02 ABSTRACT

Pain abdomen due to hyperparathyroidism is a rare condition.In hyperparathyroidism the level of parathormone hormone is raised. Parathomone is secreted from parathyroid endocrine glands which are small size(grain of rice) endocrine glands (4 in no) situated in the neck behind the thyroid. It plays an important role in calcium metabolism of body.it maintains the blood calcium level.HIGH level of this hormone in the blood leads to hypercalcemia which is responsible for many pathological conditions. Many systems and organs, such as pancreas ,kidney ,bone and brain are involved in hyperparathyroidism .It presents with pathological features of bones, stones, abdominal groans and psychic moans. Primary hyperparathyroidism during pregnancy poses significant risks to the mother and the fetus. The prevalence of primary hyperparathyroidism in the general population is 0.15%. This condition is more common in women and 25% of cases appear in women during the childbearing years. Because up to 80% of gravid patients with primary hyperparathyroidism are asymptomatic, diagnosing this condition is more difficult. Hyperparathyroidism during pregnancy puts both the mother‘s and child‘s life at risk. Complications associated with primary hyperparathyroidism in pregnancy have been reported to occur in up to 67% of mothers and 80% of fetuses. In addition to many constitutional symptoms, maternal complications include nephrolithiasis, bone disease, pancreatitis, hyperemesis, muscle weakness, mental status changes, and hypercalcemic crisis. Reported fetal complications include intrauterine growth retardation, low birth weight, preterm delivery, intrauterine fetal demise, postpartum neonatal tetany, and permanent hypoparathyroidism. . A four–fold decrease in perinatal complications may be achieved with appropriate therapy. Conservative intervention may be appropriate under certain circumstances, but excision of a parathyroid adenoma remains the only definitive treatment. Debate continues regarding the safety of surgery during pregnancy. This should be done with a minimally – invasive procedure that is as quick as possible, and of course, has a high likelihood of cure. It should be performed in the early part of the second and third trimester. Several cases of successful surgery have been reported