Background: Mesenchymal tumors originate from precursor mesodermal cells surrounding the brain parenchyma. These mesodermal cells differentiate into bone, cartilage and connective tissue(blood vessels, adipocyte, smooth muscle cells and fibroblasts), and give rise to the various CNS Mesenchymal tumors. Objective: The aim of the present study was to determine the spectrum, frequency and demographics of mesenchymal tumors at a tertiary care centre. Materials and Methods :A retrospective review of all the reported CNS mesenchymal tumors from the Department of Pathology in a period of 2.5 years from December 2017 to May 2020 was done.Results: On histopathological diagnosis , incidence of various tumors were meningioma 63.6%(359), solitary fibrous tumor/hemangiopericytoma 3.36%(n=19),Ewings/PNET 0.17%(n=1) , chondrosarcoma 0.17%(n=1), chondroma 0.17%(n=1),schwanoma 27.9%(n=158),neurofibroma 0.17%(n=1) ,Ewings sarcoma/PNET 0.17%(n=1),hemangioma 0.88%(n=5),and hemangioblastoma 18%(3.18%). Conclusions: Mesenchymal tumors occurred predominantly within 30–45 years of age with a .slight female preponderance (male to female ratio 0.68:1). Meningiomas and schwanomas were the most common mesenchymal tumor.