IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-6-25699 Original Research Paper Urolithiasis in pregnancy-Invetigations,diagnosis and management -A Review Chandra Mauli Upadhyay Dr. Dr. P. Dubey Dr. June 2020 9 6 01 02 ABSTRACT

Urinary stones are polycrystalline concretions occurring in the urinary tract of humans and animals. Like bones and teeth, they are biominerals. While the non–pathological products of biomineralization, formed in genetically determined processes, display a high degree of biological organization, uroliths are a special case. Their formation is governed by pathoanatomical and physicochemical factors . Around 97% of urinary stones are found in the kidneys and ureters (kidney stones), the remaining 3% in the urinary bladder and urethra .Between 1to15% people globally are affected at some point by urolithiasis in their life time. Urolithiasis is the most common cause of urological–related abdominal pain in pregnant women after urinary tract infection. It occurrs in 1/200 to 1/2,000 women during pregnancy, which is more or less equal to the incidence reported in the nonpregnant female population of reproductive age.Urolithiasis presenting during pregnancy is a cause of major concern, considering the potential adverse effects of radiation exposure, any invasive surgical procedures and anaesthesia on the mother and fetus.During pregnancy, the frequency of stone localization is twice as higher in the ureter than in the renal pelvis or calyx, but there is no difference between the left and right kidney or ureter. Urinary stones during pregnancy are composed mainly of calcium phosphate (hydroxyapatite) in 74% of cases and calcium oxalate in the remaining 26% (Ross et al., Urol Res 36:99–102, 2008). A significant proportion of patients with asymptomatic renal calculi are detected incidentally in the nonpregnant population compared with pregnant women. Factors that contribute to the diagnostic challenges include anatomic and physiologic changes to the female urinary tract during pregnancy and the limitations on the use of ionizing radiation. The treatment of such patients requires a multidisciplinary team approach involving the urologist, obstetrician, and radiologist. The potential hazards of intervention (either surgical or medical) and anesthesia need to be considered carefully.In conclusion, urolithiasis during pregnancy can be serious, causing preterm labor in up to 40% of affected women. Aim and objective of study: The analysis of pathogenesis, diagnosis, investigations, and management ofurolithesis in pregnancy