IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-6-25718 Original Research Paper INSULAR GLIOMAS INCLUDING VOLUMETRIC STUDY: A SINGLE INSTITUTION EXPERIENCE Uike Dr. June 2020 9 6 01 02 ABSTRACT

OBJECTIVE– Insular gliomas are difficult and challenging area to operate and manage because of its proximity to eloquent areas of the brain. Our aim is to describe and define insular glioma using MRI based volumetric study and to determine the association of overall outcome with preoperative tumor volume of insular gliomas. METHOD– The study was conducted on patients who were diagnosed as insular gliomas on MRI. All grades of patients treated by microsurgical techniques at our centre from June 2016 to December 2017 were included in the study. Volumetric scan analysis was applied on magnetic resonance images (MRIs) to establish preoperative and postoperative tumor volume. RESULT– The average age at diagnosis was 36.24 yrs; with 68% were male and 32% were female patients with the ratio of 2.13:1. 56% of patients had right sided tumor. WHO grade 2 was most common grade and constituted 62.50% of all cases followed by 20.83% had grade 4 tumor, 12.50% had grade 3 and 4.17% had grade 1 tumor. The median preoperative tumor volume was 89.72cm3. The extent of resection (EOR) <70% was 87.50% and EOR between 70–90% was 16.67% of cases. At 6 months follow up 16% patient had motor deficit, 8% had sensory deficit and 8% had language deficit. One patient died in follow up period due to the unrelated cause. CONCLUSION– A good knowledge of anatomical landmarks and awareness of potential complications can allow surgeons to reduce neurological complications and maximum safe resection of insular gliomas.