Maternal tetrahydrofolate reductase gene mutation in patients with missed abortion

Helmy A. Rady; Noha E.Mohammed; Mohammed Farag

Volume : VIII, Issue : VIII, August - 2019

Maternal tetrahydrofolate reductase gene mutation in patients with missed abortion

Helmy A. Rady, Noha E. Mohammed, Mohammed Farag

Abstract :

Background: missed abortion is a common problem, thrombophilia is a common cause of missed abortion either recurrent or not Aim of the work: to correlate presence of MTHFR gene mutation in patients with missed abortion Patients and methods: the study included 200 patients divided into 2 groups; study group included 100 patients with history of missed abortion, and control group included 100 cases with no history of missed abortion. Results: of 200 patients only 44 was having MTHFR gene mutation, 34 of them was present in case group while 10 only in control group. Conclusions: MTHFR gene mutation is a common cause of missed abortion either recurrent or not