Pregnancy Associated Breast Cancer - Review of Literature

Peoli Mukutawat; Bibhavendra Kumar Singh; Vivek Kaushal

Volume : IX, Issue : VII, July - 2020

Pregnancy Associated Breast Cancer - Review of Literature

Peoli Mukutawat, Bibhavendra Kumar Singh, Vivek Kaushal

Abstract :

Pregnancy–associated east cancer (PABC) is defined as east cancer diagnosed during pregnancy or in the first postpartum year. Breast cancer affects approximately 1 in 3000 pregnant women. Breast cancer is the second most common malignancy occurring during pregnancy worldwide, after cervical cancer. The evaluation of east cancer symptoms during pregnancy and the postpartum period can be challenging due to the hormonally induced changes in east tissue that may lead to increased firmness and nodularity. Risk factors for pregnancy induced east cancer include early age of menarche, genetic mutations (BRCA1 and BRCA2), family history, alcohol consumption and previous benign east disease. To conclude, use of surgery and chemotherapy (especially after the first trimester of pregnancy) is reasonably safe and currently modified radical mastectomy with axillary clearance followed by adjuvant chemotherapy is the treatment of choice. Radiotherapy, as a treatment modality, is not recommended till after delivery. The termination of pregnancy is not justified as it does not improve prognosis.