Sero-prevalence of herpes simplex virus type 1 and type 2 Ig G antibody among patients attending STD Outpatient Department,Tertiary Care Centre at Karaikal.

Dr Sivakumar Sivasubramaniam; Dr Tony Kuncheria

Volume : IX, Issue : V, May - 2020

Sero-prevalence of herpes simplex virus type 1 and type 2 Ig G antibody among patients attending STD Outpatient Department,Tertiary Care Centre at Karaikal.

Dr Sivakumar Sivasubramaniam, Dr Tony Kuncheria

Abstract :

Background:Infection with Herpes Simplex Virus Type–2 (HSV–2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide.There is little information on the prevalence of HSV–2 and HSV–1 in India. Methodology: Specimens were collected from 162 patients attending Vinayaka Missions STD Outpatient department and tested for HSV–1 and HSV–2 antibodies using HSV–1 and 2 Type specific IgG CLIA test kit . Data were analyzed using SPSS version 13.0. P values ≤0.05 were considered significant number. Results:Out of the 162 individuals tested, 141 (87.0%) were HSV–1 and 2 IgG positive. Infected individuals were more likely to be male than female. There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV–2 prevalence was not significantly associated with increasing age, sex, marital status, occupation, educational status, and number of sex partners(P > 0.05). Conclusions: The results highlight the potential public health impact of HSV–1 and HSV–2 in India where anti–HSV–2 and anti–HSV–1 testing is not generally performed in all populations, especially considering the risk of neonatal transmission and the attendant complications at birth.