Volume : VI, Issue : VII, July - 2017

STUDY OF SICKLE CELL DISEASE IN A TERTIARY CENTRE IN CENTRAL INDIA.

Dr. Ch. Deepak Singh, Dr. Khundrakpam Sunitarani Devi

Abstract :

 Hemoglobinopathies are disorders affecting the structure, function or production of hemoglobin. Sickle cell anemia is the most common heritable hematologic disease affecting humans.

Objectives: 1).To screen Sickle cell disorder in the age group of up to 18yrs in rural population in and around Sawangi (Meghe), Wardha. 2).To establish the role of Solubility test as screening test for detection of Sickle cell disease. 3). To compare sensitivity and specificity of Solubility test with that of Sickling test.

Material and methods: The study was carried out at the department of Pathology, Acharya Vinoba Bhave Rural Hospital, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha over a period of six months. Four hundred and forty patients up to 18yrs of age were subjected to both Solubility test and Sickling test.

Results: Out of 440 cases, both Solubility and Sickling test were positive in 40 cases (9%). Out of this 40 positive cases 28 cases (70%) were male and 12 cases (30%) were female. Number of positive cases were more i.e 16 cases (40%) in the 0–6 age groups.

Conclusion: Prevalance rate of sickle cell anemia is 9%. The ratio of male to female is 2.3:1. Maximum cases were recorded in the age group of 0–6 age groups. Sensitivity and specificity of both the test  is found to be 100%.

Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

Dr. Ch. Deepak Singh, Dr. Khundrakpam Sunitarani Devi, STUDY OF SICKLE CELL DISEASE IN A TERTIARY CENTRE IN CENTRAL INDIA., PARIPEX‾INDIAN JOURNAL OF RESEARCH : VOLUME-6 | ISSUE-7 | JULY-2017


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