TO STUDY CORRELATION OF NEUTROPHIL - LYMPHOCYTE RATIO AND DIABETIC RETIONOPATHY IN DIABETES MELLITUS TYPE 2 PATIENTS

Sagar Khandare; Ravi Kumar Patel; Sandeep Pachole

Volume : VII, Issue : X, October - 2018

TO STUDY CORRELATION OF NEUTROPHIL - LYMPHOCYTE RATIO AND DIABETIC RETIONOPATHY IN DIABETES MELLITUS TYPE 2 PATIENTS

Sagar Khandare, Ravi Kumar Patel, Sandeep Pachole

Abstract :

Introduction:Diabetic retinopathy (DR) is a microvascular complication of diabetes. Total white blood cell count is a crude but sensitive indicator of inflammation and studied in many cardiac and noncardiac diseases as an inflammatory marker such as acute myocardial infarction, stroke, and heart failure. In this study, the association of neutrophillymphocyte ratio (NLR) with DR is studied.Patients and Methods: It is an observational crosssectional study. Totally 115 diagnosed type 2 diabetes mellitus patients were registered in this study. NLR was calculated by analyzing differential leukocyte count in complete blood picture. Diabetic retinopathy was detected by doing indirect ophthalmoscopy. Results: Totally 115 diabetic patients were registered. Out of these, 83 patients had retinopathy and 32 patients did not have retinopathic changes. Mean NLR for DM2with DRis 2.49+0.94 and in DM2 without DR is 2.06 ± 0.56 whichwas highly significant (P = 0.019).Conclusion: The results of our study show that there was a significant relation between NLR and DR. Therefore, NLRmay be considered as a novel surrogate marker of DR in DM2 patients.